Gastão F. Miranda

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The inhibitory effect of nitric oxide (NO) on carotid chemosensory responses to hypoxia has been attributed in part to an antidromic inhibition of chemoreceptor cells activity. However, NO may also modulate the activity of the primary sensory neurons because NO is produced in the soma of these neurons located in the petrosal ganglion. Since a population of(More)
The Local Riemannian Manifold Learning (LRML) recovers the manifold topology and geometry behind database samples through normal coordinate neighborhoods computed by the exponential map. Besides, LRML uses barycentric coordinates to go from the parameter space to the Riemannian manifold in order to perform the manifold synthesis. Despite of the advantages(More)
The pharmacological effects of two newly synthesized anorectic agents CM 57373 (4-amino-1-(6-bromopyrid-2-yl) piperidine hydrochloride) and CM 57493 (4-(3-trifluoromethylphenyl)-1-(2-cyanoethyl)-1,2,3,6 tetrahydrophyridine hydrochloride) have been studied. Both drugs decreased food intake dose dependently in rats deprived of food for 20 h/d. The doses that(More)
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