Andreas Heyland3
Josh Sutherby3
Julia Nguyen3
Jamie-Lee Giardini3
3Andreas Heyland
3Josh Sutherby
3Julia Nguyen
3Jamie-Lee Giardini
3Mariana Leguia
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  • Michelle M Roux, Ian K Townley, Michael Raisch, Anna Reade, Cynthia Bradham, Glen Humphreys +10 others
  • 2006
The sea urchin egg has a rich history of contributions to our understanding of fundamental questions of egg activation at fertilization. Within seconds of sperm-egg interaction, calcium is released from the egg endoplasmic reticulum, launching the zygote into the mitotic cell cycle and the developmental program. The sequence of the Strongylocentrotus(More)
Improved methods are needed to reliably and accurately evaluate oocyte quality prior to fertilization and transfer into the woman of human embryos created through in vitro fertilization (IVF). All oocytes that are retrieved and matured in culture are exposed to sperm with little in the way of evaluating the oocyte quality. Furthermore, embryos created(More)
A metamorphic life-history is present in the majority of animal phyla. This developmental mode is particularly prominent among marine invertebrates with a bentho-planktonic life cycle, where a pelagic larval form transforms into a benthic adult. Metamorphic competence (the stage at which a larva is capable to undergo the metamorphic transformation and(More)
Sperm interaction with an egg in animals was first documented 160 years ago in sea urchins by Alphonse Derbès (1847) when he noted the formation of an "envelope" following the sperm's "approach" to the egg. The "envelope" in sea urchins is an obvious phenotype of fertilization in this animal and over the past 35 years has served to indicate a presence of(More)
Echinoderms (sea urchins, sea stars, brittle stars, sea lilies and sea cucumbers) are a group of diverse organisms, second in number within deuterostome species to only the chordates. Echinoderms serve as excellent model systems for developmental biology due to their diverse developmental mechanisms, tractable laboratory use, and close phylogenetic distance(More)
Isolating cells based on specific gene expression enables a focused biochemical and molecular analysis. While cultured cells and hematopoietic cells, for example, are routinely isolated by fluorescence activated cell sorting (FACS), early embryonic cells are a relatively untapped source for FACS applications often because the embryos of many animals are(More)
  • Josh Sutherby, Jamie-Lee Giardini, Julia Nguyen, Gary Wessel, Mariana Leguia, Andreas Heyland
  • 2013
In Figure six (Figure 1 here) of the original manuscript [1] panels B-H are representative images from which measurements were taken and then graphed in Figure six panel I. In the original submission of the manuscript panel C and H ended up showing identical images. We corrected this error by replacing panel C with the correct representative image. Note(More)
expression is restricted to the small micromeres of the sea urchin, but is inducible in other lineages early in development. Developmental Biology 314, no. 2: 276-286. Vasa protein expression is restricted to the small micromeres of the sea urchin, but is inducible in other lineages early in development Abstract Vasa is a DEAD-box RNA helicase that(More)