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Whole-genome sequence (WGS) data can, in principle, resolve bacterial isolates that differ by a single base pair, thus providing the highest level of discriminatory power for epidemiologic subtyping. Nonetheless, because the capability to perform whole-genome sequencing in the context of epidemiological investigations involving priority pathogens has only(More)
Neptune locates genomic signatures using an exact k-mer matching strategy while accommodating k-mer mismatches. The software identifies sequences that are sufficiently represented within " inclusion targets " and sufficiently absent from " exclusion targets ". The signature discovery process is accomplished using probabilistic models instead of heuristic(More)
Neptune locates genomic signatures using an exact k-mer matching strategy while accommodating k-mer mismatches. The software identifies sequences that are sufficiently represented within inclusion targets and sufficiently absent from exclusion targets. The signature discovery process is accomplished using probabilistic models instead of heuristic(More)
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