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  • Geoffrey I. Shapiro, Katherine M. Bell-McGuinn, +13 authors Josep Tabernero
  • Medicine
  • Clinical cancer research : an official journal of…
  • 2015 (First Published: 15 April 2015)
  • PURPOSE To evaluate safety (primary endpoint), tolerability, pharmacokinetics, pharmacodynamic profile, and preliminary activity of the intravenous, pan-class I isoform PI3K/mTOR inhibitorContinue Reading
  • T. Mok, David Robert Spigel, +7 authors Pasi A. Jänne
  • Medicine
  • 2010 (First Published: 20 May 2010)
  • 7537 Background: Efficacy of gefitinib as first-line tx of adv NSCLC with epidermal growth factor receptor (EGFR) mutation (mu) has been shown in a phase (P) 3 trial. PF299 shows preclinical activityContinue Reading