Gary Sommerville

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Experiments have been conducted on human subjects to assess the efficiency with which a helmet-mounted sighting system can be used to locate and track target sources in the horizontal plane. In the first experimental condition, in which the sight was aligned with discrete stationary target sources, the latency between target presentation and final target(More)
Resistance to neoadjuvant chemoradiation therapy (CRT) remains a critical barrier to the effective treatment of esophageal adenocarcinoma (EAC). Cancer stem-like cells (CSCs) are a distinct subpopulation of cells implicated in the resistance of tumors to anti-cancer therapy. However, their role in the resistance of EAC to CRT is largely unknown. In this(More)
Oncogenic mutations in BRAF are common in melanoma and thyroid carcinoma and drive constitutive activation of the MAPK pathway. Molecularly targeted therapies of this pathway improves survival compared to chemotherapy; however, responses tend to be short-lived as resistance invariably occursCell line models of melanoma and thyroid carcinoma, +/- BRAF(V600E)(More)
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