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Studies of tissue cell locomotion in culture have revealed much about cell motility, but whether behaviour in vitro resembles movement of the same cells in the animal is not clear. To investigate this, I compared the locomotion and cell-substratum contacts of epidermal cells from Xenopus tadpoles, migrating from explants on glass and plastic, with the same(More)
In amphibians, the composition and pattern of expression of the myosin heavy chain (myHC) gene family are mostly unknown. To understand better the regulation of this complex family, we screened cDNA libraries from swimming tadpole and adult leg muscle RNA and have isolated and partially sequenced clones for several myHCs. Two of these, E3 and E19, first(More)
Vertebrate skeletal muscles contain a family of myosin heavy chain (MyHC) proteins whose expression varies with clonal origin, developmental age, hormonal state, and innervation patterns. The number of MyHC genes and their regulation have been intensely studied in mammals and birds. However, Comparatively little is known about MyHC expression in other(More)
High grade superficial TCC of the bladder (T1 G3) has an important risk of recurrence and/or progression (40%) after TUR-B and a low survival rate (57% at 3 years, 50% at 10 years). Intravescical treatment with BCG seems to be able to reduce these rates. 64 patients with T1 G3 vescical TCC underwent a "second look" TUR-B. 9/64 patients presented locally(More)
THE TOXICITY OF CADMIUM TO THE AQUATIC AMPHIBIAN, Xenopus laevis Sharon Suzanne Millirons Master of Science in Biology University of Richmond Dr. Gary Paul Radice, Thesis Advisor Cadmium toxicity is poorly understood but is a potentially serious environmental pollutant. This study was initiated to determine the effect of significant concentrations of(More)
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