Learn More
A protein lethal to mice was isolated from the sea nettle (Chrysaora quinquecirrha) mesenteric tentacle nematocysts by immunochromatography. The partially purified protein was also toxic to spontaneously beating cultural chick cardiocytes but was not hemolytic to rat erythrocytes. On sodium dodecyl sulfate polyacrylamide gels, the mesenteric protein(More)
Ten years have elapsed since our last review article on the toxicology of venomous pelagic coelenterates was published (Burnett and Calton, 1977). Investigation on important medusae and the chemistry of their nematocyst venoms have been expanding. The venomous jellyfish discussed here include the Portuguese man-o'war, (Physalia physalis), the sea nettle(More)
The effect of borohydride reducing reagents on monoclonal and polyclonal antibodies was examined by enzyme-linked immunosorbent assay (ELISA). Each antibody showed different stability characteristics to the reducing reagents. Sodium cyanoborohydride was at least five times milder toward immunological activity than sodium borohydride, however, sodium(More)
Whole cells of Escherichia coli containing aspartase activity were immobilized by mixing a cell suspension with a liquid isocyanate-capped polyurethane prepolymer (Hypol). The immobilized cell preparation was used to convert ammonium fumarate to l-aspartic acid. Properties of the immobilized E. coli cells containing aspartase were investigated with a batch(More)
Jellyfish venoms are complex mixtures of polypeptides and enzymes pathogenic to man by means of their toxic or antigenic properties. With newer technology, more therapeutic agents will become available to treat the various envenomation syndromes caused by these animals. It will therefore be necessary to make an accurate diagnosis of the type of reaction the(More)
To determine a reliable first aid topical remedy for jellyfish stings, we investigated several commonly available preparations to determine their ability to prevent nematocyst rupture from sea nettle (Chrysaora quinquecirrha) and Portuguese man-of-war (Physalia physalis) tentacles. The application of a baking soda slurry was a good inhibitor of nematocyst(More)
A randomized double-blind trial to evaluate the safety of a novel recombinant virus, ICP10deltaPK, for reduction or prevention of recurrent herpes simplex virus type 2 (HSV-2) infection was carried out in public hospitals in Mexico City. Persons having a minimum of 5 documented herpetic recurrences in the previous year were randomized for vaccination.(More)