Gary H Murray

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BACKGROUND Gabapentin is widely approved as add-on therapy for epilepsy treatment for partial seizures with and without secondary generalization. To investigate the efficacy of gabapentin administered as monotherapy in patients with newly diagnosed partial epilepsy, a randomized double-blind trial was performed. METHODS Eligible patients were randomized(More)
PURPOSE To evaluate the efficacy and safety of gabapentin (Neurontin; GBP) as add-on therapy for refractory partial seizures in paediatric patients aged 3-12 years. METHODS After a 6-week baseline period, 247 patients (54 centres) entered a 12-week double-blind phase and were randomized to receive either GBP (t.i.d., titrated to 23-35 mg/kg/ day) or(More)
Several different techniques exist for sharpening periodontal scalers each of which will yield a relatively sharp instrument; however, some techniques may decrease the strength of the instrument more rapidly than others. The purpose of this study was to evaluate the effect of two different sharpening techniques on the strength of a periodontal scaler. Sixty(More)
Rolipram is an antidepressant with a novel mechanism of action: enhanced noradrenaline (first messenger) synthesis and release, and inhibition of cAMP (second messenger) breakdown. This study was aimed at objectively assessing potential anticholinergic effects of rolipram in healthy elderly volunteers by measurement of saliva production and pupil size.(More)
The Air Force Dental Service was founded shortly after World War II in order to provide oral health care to active duty, retired, and active reserve Air Force personnel, their families while overseas, and designated others. Grouped with medical facilities and organized by functional commands, the Air Force Dental Service enjoys a strong reputation in(More)
The efficacy and safety of gabapentin as add-on therapy for refractory partial seizures in 237 children, aged 3 to 12 years were evaluated over a 6-month period. All children received gabapentin at 24 to 70 mg/kg/day. Efficacy variables included the percent change in seizure frequency and the responder rate (defined as those patients who showed >50%(More)
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