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  • William Chad Stanley, Gary D Lopaschuk, James L. Hall, James G. Mccormack
  • Biology, Medicine
  • Cardiovascular research
  • 1997 (First Publication: 1 February 1997)
  • It is now clear that the availability of different metabolic substrates can have a profound influence on the extent of damage incurred during episodes of cardiac ischaemia, and on cardiac functionalExpand
  • Naomi Kudo, Amy J. Barr, Rick L. Barr, S Desai, Gary D Lopaschuk
  • Biology, Medicine
  • The Journal of Biological Chemistry
  • 1995 (First Publication: 21 July 1995)
  • We determined whether high fatty acid oxidation rates during aerobic reperfusion of ischemic hearts could be explained by a decrease in malonyl-CoA levels, which would relieve inhibition of carnitineExpand
  • Paul F. Kantor, Arnaud Lucien, Ray Kozak, Gary D Lopaschuk
  • Chemistry, Medicine
  • Circulation research
  • 2000 (First Publication: 17 March 2000)
  • Trimetazidine is a clinically effective antianginal agent that has no negative inotropic or vasodilator properties. Although it is thought to have direct cytoprotective actions on the myocardium, theExpand