Gary A. Eiceman

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Ion mobility spectrometry has become the most successful and widely used technology for the detection of trace levels of nitro-organic explosives on handbags and carry on-luggage in airports throughout the US. The low detection limits are provided by the efficient ionization process, namely, atmospheric pressure chemical ionization (APCI) reactions in(More)
Trends in the development of ion mobility spectrometry are reviewed. A discussion of general principles of operation includes an overview and examines drift tube technology and ionization and response. A discussion of the scope of applications examines detection and characterization of single substances and complex mixtures. The technology that permitted(More)
Normal and cyclic alkanes and alkenes form stable gas-phase ions in air at atmospheric pressure from 40 to 200°C when moisture is below 1 ppm. Ionization of alkanes in a (63)Ni source favored charge transfer over proton transfer through pathways involving [M-1](+) and [M-3](+) ions. Ion mobility spectra for alkanes showed sharp and symmetrical profiles(More)
Differential mobility spectrometry (DMS) of nitro-organic explosives and related compounds exhibited the expected product ions of M- or M x NO2- from atmospheric pressure chemical ionization reactions in purified air at 100 degrees C. Peaks in the differential mobility spectra for these ions were confined to a narrow range of compensation voltages between(More)
The dependence of the mobilities of gas-phase ions on electric fields from 0 to 90 Td at ambient pressure was determined for protonated monomers [(MH+(H2O)n] and proton bound dimers [M2H+(H2O)n] for a homologous series of normal ketones, from acetone to decanone (M=C3H6O to C10H20O). This dependence was measured as the normalized function of mobility alpha(More)
A microfabricated planar differential ion mobility spectrometer operating from 0.4 to 1.55 atm in a supporting atmosphere of purified air was used to characterize the effects of pressure and electric field strength on compensation voltage, ion transmission, peak width, and peak intensity in differential mobility spectra. Peak positions, in compensation(More)
Hydrazine (HZ) and monomethylhydrazine (MMH) in air were monitored continuously using a hand-held ion mobility spectrometer equipped with membrane inlet, 63Ni ion source, acetone reagent gas, and ambient temperature drift tube. Response characteristics included detection limit, 6 ppb; linear range, 10-600 ppb; saturated response, >2 ppm; and stable(More)
Differential mobility spectra for alkanes, alcohols, ketones, cycloalkanes, substituted ketones, and substituted benzenes with carbon numbers between 3 and 10 were obtained from gas chromatography-differential mobility spectrometry (GC-DMS) analyses of mixtures in dilute solution. Spectra were produced in a supporting atmosphere of purified air with 0.6-0.8(More)