Gargi Sur

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Galax is a lightweight , portable, open-source implementation of XQuery 1.0. Started in Decem-ber 2000 as a small prototype designed to test the XQuery static type system, Galax has now become a solid implementation, aiming at full conformance with the family of XQuery 1.0 specifications. Because of its completeness and open architecture , Galax also turns(More)
BACKGROUND Progressive multifocal leukoencephalopathy (PML) in natalizumab-treated MS patients is linked to JC virus (JCV) infection. JCV sequence variation and rearrangements influence viral pathogenicity and tropism. To better understand PML development, we analyzed viral DNA sequences in blood, CSF and/or urine of natalizumab-treated PML patients. (More)
  • Keith A. Wharton, Catherine Quigley, Marian Themeles, Robert W. Dunstan, Kathryn Doyle, Ellen Cahir-McFarland +13 others
  • 2016
Over half of adults are seropositive for JC polyomavirus (JCV), but rare individuals develop progressive multifocal leukoencephalopathy (PML), a demyelinating JCV infection of the central nervous system. Previously, PML was primarily seen in immunosuppressed patients with AIDS or certain cancers, but it has recently emerged as a drug safety issue through(More)
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