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Mutations in the MECP2 gene cause Rett syndrome (RTT). Bdnf is a MeCP2 target gene; however, its role in RTT pathogenesis is unknown. We examined Bdnf conditional mutant mice for RTT-relevant pathologies and observed that loss of BDNF caused smaller brain size, smaller CA2 neurons, smaller glomerulus size, and a characteristic hindlimb-clasping phenotype.(More)
PURPOSE To determine the effect of eye dominance on the nature of perceived eye contact and perceived eye misalignment. METHODS In this experimental study, strabismic and nonstrabismic human subjects over the age of 18 were assessed for strength of eye dominance, being classified as either weakly or strongly dominant. They were asked whether they(More)
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