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OBJECTIVE To investigate trends in the incidence of adenocarcinoma (AC) of the oesophagus in New South Wales, factors associated with a diagnosis of AC, and factors associated with survival of patients with AC. DESIGN AND SETTING We examined all cases of invasive oesophageal cancer recorded in the NSW Central Cancer Registry from 1972 to 2005. The(More)
BACKGROUND Dysphagia following laparoscopic paraesophageal hernia repair is an uncommon but difficult problem that may be due to technical factors. We looked for an association between esophageal angulation after posterior crural repair and postoperative dysphagia. MATERIALS AND METHODS Patients undergoing paraesophageal hiatus hernia repair were(More)
BACKGROUND Maximal cardiopulmonary exercise testing (CPX) is valuable to quantifying functional capacity in patients with pulmonary hypertension (PH), but information on CPX in children is limited possibly because of safety concerns. The purpose of this study was to examine the safety of CPX in pediatric patients with PH. METHODS Data were obtained(More)
OBJECTIVE To describe the associations between physical disability measures and knee cartilage defects in obese adults. METHODS One hundred and eleven obese subjects were recruited from laparoscopic adjustable gastric banding or exercise/diet weight loss programmes. All subjects completed disease-specific (WOMAC) and general health status (SF-36)(More)
BACKGROUND Most studies analyzing risk factors for pulmonary morbidity date from the early 1990s. Changes in technology and treatment such as minimally invasive esophagectomy (MIE) and neoadjuvant treatment mandate analysis of more contemporary cohorts. METHODS Predictive factors for overall and specific pulmonary morbidity in 858 patients undergoing(More)
The aim of this study was to determine health-related quality of life and fatigue measures in obese subjects and to compare scores with age- and gender-matched population norms. A total of 163 obese subjects were recruited from laparoscopic-adjustable gastric banding or exercise and diet weight loss programs between March 2006 and December 2007. All(More)
Primary repair of large hiatal defects is associated with higher than acceptable recurrence rates. This has led to the increased use of fascial prostheses for reinforcement of the hiatal repair. We report a case of intraluminal mesh erosion after repair of a recurrent paraesophageal hernia with a composite polytetrafluoroethylene/expanded(More)
Laparoscopic fundoplication has become the standard operation for gastroesophageal reflux disease. In our service, a laparoscopic fundoplication is performed as a 2-cm floppy 360 degrees wrap with division of the short gastric vessels and the fundoplication is sutured using a prolene 2/0 mattress suture (Ethicon, USA) and buttressed laterally with two(More)
BACKGROUND Obesity is an important risk factor for knee osteoarthritis (OA), Weight loss can reduce the symptoms of knee OA. No prospective studies assessing the impact of weight loss on knee cartilage structure and composition have been performed. OBJECTIVES To assess the impact of weight loss on knee cartilage thickness and composition. METHODS 111(More)