Gareth T. Davies

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The telecommunications industry is going through a technological revolution, involving a transition from multiple voice and data networks to integrated service networks using packet switching technologies. The paper describes a new framework (the IPCP Framework) for capacity planning and costing in an IP network environment. Capacity Planning is carried out(More)
We construct secret-key encryption (SKE) schemes that are secure against related-key attacks and in the presence of key-dependent messages (RKA-KDM secure). We emphasize that RKA-KDM security is not merely the conjunction of individual security properties, but covers attacks in which ciphertexts of key-dependent messages under related keys are available.(More)
Results Context Investigated KDM Security in the context of Hybrid Encryption: § Present a generic composition theorem for adaptive, KDM-secure hybrid encryption in the Random Oracle model. § Proof method incorporates non-standard techniques that could be applicable in a wider context. Key-Dependent Message (KDM) Security involves an environment where the(More)
TNFα (tumour necrosis factor α) is an early mediator in the systemic inflammatory response to infection and is therefore a therapeutic target in sepsis. AZD9773 is an ovine-derived, polyclonal anti-TNFα Fab fragment derived from a pool of serum and currently being developed as a treatment for severe sepsis and septic shock. In the present study, we show(More)
We construct secret-key encryption (SKE) schemes that are secure against related-key attacks and in the presence of key-dependent messages (RKA-KDM secure). We emphasize that RKA-KDM security is not merely the conjunction of individual security properties, but covers attacks in which ciphertexts of key-dependent messages under related keys are available.(More)
Protein tyrosine kinases differ widely in their propensity to undergo rearrangements of the N-terminal Asp-Phe-Gly (DFG) motif of the activation loop, with some, including FGFR1 kinase, appearing refractory to this so-called 'DFG flip'. Recent inhibitor-bound structures have unexpectedly revealed FGFR1 for the first time in a 'DFG-out' state. Here we use(More)
Surface plasmon resonance (SPR) is a powerful method for obtaining detailed molecular interaction parameters. Modern instrumentation with its increased throughput has enabled routine screening by SPR in hit-to-lead and lead optimization programs, and SPR has become a mainstream drug discovery technology. However, the processing and reporting of SPR data in(More)
Deduplication removes redundant copies of files or data blocks stored on the cloud. Client-side deduplication, where the client only uploads the file upon the request of the server, provides major storage and bandwidth savings, but introduces a number of security concerns. Harnik et al. (2010) showed how cross-user client-side deduplication inherently gives(More)
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