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OBJECTIVE What underlies the protection of estrogen against spinal cord injury remains largely unclear. Here, we investigated the expression pattern of a new estrogen receptor, G-protein coupled estrogen receptor 1 in the spinal cord and its role in estrogenic protection against spinal cord injury. DESIGN AND SETTINGS Department of Neurosurgery and Key(More)
OBJECTIVES Hypobaric hypoxia at high altitude can lead to brain damage and pre-conditioning with hyperbaric oxygen (HBO) can reduce ischemic/hypoxic brain injury. This study investigates the effects of high altitude on traumatic brain injury (TBI) and examines the neuroprotection provided by HBO preconditioning against TBI. METHODS Rats were randomly(More)
PURPOSE We reviewed the clinical and follow-up data of 89 cases with cerebral paragonimiasis and summarized the disease characteristics, diagnostic strategies and treatment experience, with an expectation of establishing standard diagnosis and treatment for cerebral paragonimiasis. METHODS A total of 89 cases (age: 2-64 years) of cerebral paragonimiasis(More)
The authors report a 21-year-old male with an atypical cystic meningioma in the right parietal area. On T1-weighted imaging (T1WI), the solid component was hypointense, while on T2-weighted imaging (T2WI), it was hyperintense. On T1WI, the cystic component was hypointense, and on T2WI, it was hyperintense. The authors review the literature about incidence,(More)
Neural stem/progenitor cells (NSPCs) replacement therapies are the most attractive strategies to restore an injured brain. Key challenges of such therapies are enriching NSPCs and directing them differentiation into specific neural cell types. Here, three biomaterial substrates Poly-L-ornithine (PO), Poly-L-lysine (PLL) and fibronectin (FN) were(More)
OBJECTIVE To build digitized visible model of the parapharyngeal space(PPS) of Chinese visible human. METHOD Cross-sectional images from the Chinese visible human data set were reviewed and the structures of the parapharyngeal space were confirmed on a section-by-section basis. Three-dimensional computer reconstructions of the parapharyngeal space and(More)
Emerging studies have demonstrated the important physiological and pathophysiological roles of hydrogen sulphide (H2S) as a gasotransmitter for NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome-associated neuroinflammation in the central nervous system. However, the effects of H2S on neuroinflammation after intracerebral haemorrhage(More)
Previously, it was widely accepted that the delayed ischemic injury and poor clinical outcome following subarachnoid hemorrhage (SAH) was caused by cerebral vasospasm. This classical theory was challenged by a clazosentan clinical trial, which failed to improve patient outcome, despite reversing angiographic vasospasm. One possible explanation for the(More)
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