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Bacteria of the order Rickettsiales (Alphaproteobacteria) are obligate intracellular parasites that infect species from virtually every major eukaryotic lineage. Several rickettsial genera harbor species that are significant emerging and re-emerging pathogens of humans. As species of Rickettsiales are associated with an extremely diverse host range, a(More)
To better understand the pathogenicity and infectivity of a natural reassortant CGRn9415 generated from Hantaan virus (HTNV) and Seoul virus (SEOV), CGRn9415, HTNV 76-118 and SEOV L99 were used to infect newborn Kunming (KM) mice and newborn Wistar rats. In KM mice, there was no statistical difference between the death rate with CGRn9415 and that of L99,(More)
The first acylmethyl(hydroxymethyl)pyridine ligand-containing [Fe]hydrogenase model complexes 2-4 have been synthesized starting from the nucleophilic substitution reaction of 2-(4-MeC(6)H(4)SO(3)CH(2))-6-HOCH(2)C(5)H(3)N with Na(2)Fe(CO)(4). While the reaction course for producing complex 3 via the highly unstable intermediate complex 1 is monitored by in(More)
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