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Recently, activated microglia have been shown to be involved in the regulation of several aspects of neurogenesis under certain experimental conditions both in vitro and in vivo. A neurogenesis supportive microglia phenotype has been suggested to arise from the interaction of microglia with homing encephalitogenic T cells. However, a unified hypothesis(More)
Stathmin (Oncoprotein18), a ubiquitous and highly conserved 19-kDa cytosolic phosphoprotein, has been reported to play a critical role in mitosis and possibly other cellular processes, which is associated with tumor carcinogenesis and development. The purpose of this study was to examine the involvement of stathmin in human cervical carcinogenesis and to(More)
E-cadherin plays a crucial role in epithelial cell-cell adhesion and in the maintenance of tissue architecture. Down-regulation of E-cadherin expression correlates with a strong invasive potential, resulting in poor prognosis in many human carcinomas, including breast cancer. Restoration of E-cadherin can inhibit cell invasion and metastasis in many types(More)
UHRF1, also known as ICBP90 (inverted CCAAT box binding protein 90) in human, is a nuclear protein that acts as a fundamental regulator in cell proliferation and maintains DNA methylation. It is reported that UHRF1 is obviously upregulated in various human malignancies, but unchanged in differentiated tissues, suggesting that UHRF1 plays a crucial role in(More)
Stathmin is overexpressed in a variety of assessed human malignancies and is correlated with tumor progression and poor prognosis. Downregulation of its expression will contribute to optimize therapeutic outcomes in the treatment of various malignancies. However, the mechanisms of stathmin gene overexpression are not completely elucidated at present. Early(More)
Under the pressure of air pollution and oil shortage of transportations, hydrogen as a renewable and clean energy gets more and more attentions from all over the world. There predicts that the 21 century will be a hydrogen century. Nowadays, for the cost and not matured technology of fuel cell stack, hybrid system becomes the best solution. For a 5-ton fuel(More)
The article constructs the quantitative model for sport training quality monitor by using Analytic Hierarchy Process method. The first level indicators of quantitative monitor model are the training effect, training process, training load, preparation before class and training attitude, the second level indicators are 17 items in total. By testing the(More)
In recent years, accidents of urban large scale sewage treatment plant at home and abroad have took a big loss to countries and individuals. Based on field research and scientific analysis of one large sewage treatment plant this paper use the safety check list to evaluate its safety and get that the main risk factors which should be focused on are(More)
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