Gantao Chen

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The objective of this study is to explore the role of hypoxia inducible factor-1 (HIF-1) in glycolysis activity and its relationship with malignant biologic behaviors of cervical cancer. Immunohistochemistry was performed to study the protein expression and distribution of HIF-1α and glucose transport protein 1 (GLUT1) in cervical tissue of 158 cases,(More)
Cervical cancer is a leading cause of morbidity and mortality in women worldwide. Hydroxycamptothecin (HCPT) represents a new generation of antitumor agents targeting DNA topoisomerase I, which has been applied to treat various cancers with fewer side effects. Autophagy is emerging as an important biological mechanism in targeting human cancers, including(More)
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