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MOTIVATION The complete sequencing of many genomes has made it possible to identify orthologous genes descending from a common ancestor. However, reconstruction of evolutionary history over long time periods faces many challenges due to gene duplications and losses. Identification of orthologous groups shared by multiple proteomes therefore becomes a(More)
We present a new algorithm, A*Prune, to list (in order of increasing length) the first K Multiple-Constrained-Shortest-Path (KMCSP) between a given pair of nodes in a digraph in which each arc is associated with multiple Quality-of-Service (QoS) metrics. The algorithm constructs paths starting at the source and going towards the destination. But, at each(More)
This paper presents a broadband very low 3<sup>rd</sup> -order intermodulation inductor-less low-noise amplifier (LNA) implemented in 0.13 mum CMOS technology. The LNA consists of a common-gate input stage for wideband impedance matching, followed by two parallel common source amplifiers which perform noise and distortion cancellation. Third-order(More)
A novel framework using a Bayesian approach for content-based phishing web page detection is presented. Our model takes into account textual and visual contents to measure the similarity between the protected web page and suspicious web pages. A text classifier, an image classifier, and an algorithm fusing the results from classifiers are introduced. An(More)
Guo Zhang1,2,3,4, Juxue Li1,2,3,4, Sudarshana Purkayastha1,2,3,4, Yizhe Tang1,2,3,4, Hai Zhang1,2,3,4, Ye Yin1,2,3, Bo Li1,2,3, Gang Liu1,2,3, and Dongsheng Cai1,2,3,* 1Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY 10461 2Diabetes Research Center, Albert Einstein College of Medicine, Bronx, NY 10461 3Institute of(More)
The molecular mechanism underlying cancer invasiveness and metastasis of gastric carcinoma remains elusive. Here, we reported significant decrease in microRNA (miRNA)-34a and significant increase in phosphorylated epidermal growth factor receptor (EGFR) and matrix metalloproteinase-7 (MMP7) in the resected gastric carcinoma from the patients, compared with(More)
This study assessed in vivo temporal and spatial electrophysiological properties of murine hearts and the effect of manipulation of transmural action potential durations (APDs) on T wave morphology. Monophasic action potentials (MAPs) were acquired from multiple left ventricular sites. All MAPs exhibited a plateau phase, with a spike and dome appearance(More)
BACKGROUND The recently published histopathologic classification of antineutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis might greatly aid in the prognostication of patients at the time of diagnosis. This study aims to re-evaluate the new classification for its prognostic capacity in an independent Chinese series. METHODS One hundred(More)
Tumor invasion and metastasis are the main causes of death from cancer. Epithelial to mesenchymal transition (EMT) is a determining step for a cancer cell to progress from a noninvasive to invasive state. Krüppel-like factor 8 (KLF8) plays a key role in oncogenic transformation and is highly overexpressed in several types of invasive human cancer, including(More)