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An elevated serum titer of immunoglobulin G4 (IgG4), the least common (3% to 6%) of the 4 subclasses of IgG, is a surrogate marker for the recently characterized IgG4-related sclerosing disease. The syndrome affects predominantly middle-aged and elderly patients, with male predominance. The patients present with symptoms referable to the involvement of 1 or(More)
Data analysis is an important functionality in cloud computing which allows a huge amount of data to be processed over very large clusters. MapReduce is recognized as a popular way to handle data in the cloud environment due to its excellent scalability and good fault tolerance. However, compared to parallel databases, the performance of MapReduce is slower(More)
With the explosive growth of microblogging services, short-text messages (also known as tweets) are being created and shared at an unprecedented rate. Tweets in its raw form can be incredibly informative, but also overwhelming. For both end-users and data analysts it is a nightmare to plow through millions of tweets which contain enormous noises and(More)
Growing main memory capacity has fueled the development of in-memory big data management and processing. By eliminating disk I/O bottleneck, it is now possible to support interactive data analytics. However, in-memory systems are much more sensitive to other sources of overhead that do not matter in traditional I/O-bounded disk-based systems. Some issues(More)
The emerging location-based social network (LBSN) services not only allow people to maintain cyber links with their friends, but also enable them to share the events happening on them at different locations. The geo-social correlations among event participants make it possible to quantify mutual user influence for various events. Such a quantification of(More)
Personalized web search (PWS) has demonstrated its effectiveness in improving the quality of various search services on the Internet. However, evidences show that users' reluctance to disclose their private information during search has become a major barrier for the wide proliferation of PWS. We study privacy protection in PWS applications that model user(More)
BACKGROUND Coronaviruses such as severe acute respiratory syndrome (SARS) coronavirus (SCoV) and mouse hepatitis virus A59 (MHV-A59) have evolved strategies to disable the innate immune system for productive replication and spread of infection. We have previously shown that papain-like protease domain 2 (PLP2), a catalytic domain of the nonstructural(More)
Distributed graph processing systems increasingly require many compute nodes to cope with the requirements imposed by contemporary graph-based Big Data applications. However, increasing the number of compute nodes increases the chance of node failures. Therefore, provisioning an efficient failure recovery strategy is critical for distributed graph(More)
Infections by coronaviruses such as severe acute respiratory syndrome (SARS) coronavirus (SCoV) and mouse hepatitis virus A59 (MHV-A59) result in very little type I interferon (IFN) production by host cells, which is potentially responsible for the rapid viral growth and severe immunopathology associated with SARS. However, the molecular mechanisms for the(More)
PURPOSE Currently, nasopharyngeal carcinoma (NPC) prognosis evaluation is based primarily on the TNM staging system. This study aims to identify prognostic markers for NPC. PATIENTS AND METHODS We detected expression of 18 biomarkers by immunohistochemistry in NPC tumors from 209 patients and evaluated the association between gene expression level and(More)