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BACKGROUND Cellular response to chemotherapeutic drugs in the absence of BRCA1 either completely or partially had drawn less attention. The present study evaluated whether there is a differential(More)
Abstract Purpose: The Bcl-2 family of proteins regulates a late step in the apoptosis pathway. Bcl-2 protein is believed to be involved in imparting resistance to programmed cell death or apoptosis(More)
Acute lymphoblastic leukemia (ALL) is the most frequent childhood tumor. Although the cure rate has increased dramatically over the past few years, the molecular and cellular biology of this disease(More)