Ganapathy Krishnan

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The human opportunistic pathogen Pseudomonas aeruginosa strain PA14 infects both plants and animals. Previously, using plants to screen directly for P. aeruginosa virulence-attenuated mutants, we identified a locus, pho34B12, relevant in mammalian pathogenesis. Here, nonsense point mutations in the two opposing ORFs identified in the pho34B12 locus revealed(More)
The type 1 domain of thyroglobulin is a protein module (Thyr-1) that occurs in a variety of secreted and membrane proteins. Several examples of Thyr-1 modules have been previously identified as inhibitors of the papain family of cysteine proteinases. Saxiphilin is a neurotoxin-binding protein from bullfrog and a homolog of transferrin with a pair of such(More)
A study of Optical Character Recognition (OCR) techniques employed in automatic mail sorting equipment is presented. Methods and algorithms for image preprocessing, character recognition, and contextual postprocessing are discussed and compared. The objective of the study is to provide a background in the state-of-the-art of this equipment as the first(More)
Saxiphilin is a plasma protein from the bullfrog (Rana catesbiana) that binds saxitoxin (STX), a causative agent of paralytic shellfish poisoning. Saxiphilin is homologous to transferrin and consists of two internally homologous domains called the N-lobe and the C-lobe. STX binds to a single site in the C-lobe of saxiphilin. In this study, cloned genes(More)
A Perceptual Significance Hierarchy (PSH) for line art images is developed which represents the relative perceptual significance of each image component. This is possible through the use of a set of image-features which are used by the human visual system. The PSH and related rho-space computer vrsion algorithms can be used to automate the fake color(More)
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