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Cancer chemotherapy resistance (MDR) is the innate and/or acquired ability of cancer cells to evade the effects of chemotherapeutics and is one of the most pressing major dilemmas in cancer therapy. Chemotherapy resistance can arise due to several host or tumor-related factors. However, most current research is focused on tumor-specific factors and… (More)
[This corrects the article on p. 777 in vol. 1, PMID: 25621294.].
Carcinogenesis occurs through a series of steps from normal into benign and finally malignant phenotype. This cancer evolutionary trajectory has been accompanied by similar metabolic transformation from normal metabolism into Pasteur and/or Crabtree-Effects into Warburg-Effect and finally Cannibalism and/or Lactate-Symbiosis. Due to lactate production as an… (More)
Diclofenac Sodium is a Non-steroidal Anti-inflammatory Drug commonly used for the treatment of Rheumatoid arthritis, Osteoarthritis, Ankylosing Spondylitis and Periarticular disorders. In this work 100 mgs of Diclofenac sodium Tablets were prepared by Direct Compression method. Pre & Post compression studies were carried out followed by In vitro release… (More)