Galicia Davila

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BACKGROUND Immediate hypersensitivity reactions to clavulanic acid (CLV) seem to be on the increase. Diagnosis is mainly based on skin testing and the drug provocation test (DPT), procedures that are not risk free. The aim of this study was to evaluate whether the histamine release test (HRT) could help evaluate patients with selective hypersensitivity to(More)
Methods Nineteen patients with an immediate hypersensitivity reaction after AX-CLV administration were evaluated. Skin tests were done with PPL, DM, AX and CLV (DIATER, Madrid, Spain). Controls (n=21) with proven AX-CLV tolerance were included in the context of a Spanish cross-sectional multicentric study including five hospitals. In vitro tests were(More)
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