Gale Ramsby

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Periventricular heterotopia (PH) involves dramatic malformations of the human cerebral cortex. Here we show that PH is closely linked to markers in distal Xq28 (maximal two-point lod score = 4.77 for F8C at theta = 0; maximal multipoint lod score = 5.37), so that affected females are obligatory mosaics for the mutation; that PH is lethal to at least some(More)
OBJECTIVE To define the evolution of identified high-signal brain parenchymal lesions on magnetic resonance imaging (MRI) studies in patients with neurofibromatosis type 1 (NF-1). DESIGN A cohort of patients with NF-1 who underwent MRI were identified prospectively and their imaging studies analyzed. PATIENTS All referred patients with NF-1 (as defined(More)
We report the clinical and neuroimaging findings of a mother and daughter with seizure disorders and band heterotopias seen on magnetic resonance imaging studies. These clinicoradiologic findings simulate those for a diagnosis of tuberous sclerosis complex. Clinicians should be aware of this migrational anomaly and its neuroimaging characteristics, as well(More)
RATIONALE AND OBJECTIVES We undertook an MRI brain morphometric analysis to investigate the relationships between brain and skull base growth and clinical function in patients with achondroplasia as compared to normal controls. METHODS Patients selected for evaluation included pediatric patients who underwent T1 and T2 or dual-echo, proton-density axial(More)
The effectiveness of five cervical orthoses in restricting cervical motion was evaluated quantitatively in normal subjects using roentgenograms and overhead photographs made at the extremes of three planes of motion, while the effectiveness of the halo with a plastic body-vest was studied in seven patients with cervical fractures or local fusions. Flexion(More)
RATIONALE AND OBJECTIVES To investigate the relationships between brain and skull base growth in patients with neurofibromatosis 1 (NF1) compared with healthy control subjects using brain magnetic resonance imaging (MRI) for morphometric analysis. METHODS Evaluated patients included children who underwent T1- and T2-weighted or dual-echo proton density(More)
RATIONALE AND OBJECTIVES The authors performed this study to investigate the verification of the contrast display properties defined by the digital imaging and communication in medicine (DICOM) PS (picture archiving and communication system [PACS] standard) 3.14-2001 gray-scale display function standard and their dependency on display luminance range and(More)
The purpose of this study was to determine the locations and characterize the types of brain abnormalities noted on brain magnetic resonance imaging in patients with probable and definite neurofibromatosis type 1. Patients with definite neurofibromatosis type 1 (n = 17) were studied when clinically indicated, and patients with probable neurofibromatosis(More)
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