Gaku Yamamoto

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Multi-agent systems can be viewed as systems in which large numbers of agents process jobs by interacting with each other. We have been applying such a multi-agent system to electronic commerce (EC) on the Internet since December 1997. Since the server on the system has to host thousands of agents that process jobs in a disorderly manner, the mechanism for(More)
BACKGROUND Ezrin is a member of the ezrin, radixin, and moesin family that provides a functional link between the plasma membrane and the cortical actin cytoskeleton. A correlation between ezrin overexpression and aggressive cancer behavior has been recently reported in various tumor types. However, its roles in the mechanisms underlying progression of(More)
Recently Web sites have been providing users with services in accordance with their preference data. In addition to such configuration services, notification services, which process jobs in response to events which occurred at a server in the users' absence, and asynchronous services, which perform jobs after users submit requests, are also available. An(More)
There are many studies on ABS and several frameworks for ABS have already been published. However, there are few frameworks that can enable agent-based simulation using large numbers of agents. We have been developing a Java-based platform for Massive Agent-Based Simulation (MABS) called "Zillions of Agents-based Simulation Environment" or ZASE. The purpose(More)
INTRODUCTION Recombinant human bone morphogenetic protein-2 (rh-BMP2) has osteoinductive properties. The sequence of osteogenesis induced by rh-BMP2 in a rat calvarial bone defect model was evaluated histologically. MATERIAL AND METHODS Atelopeptide type I collagen was selected as the carrier matrix for rh-BMP2. This collagen was mixed with 50 microg of(More)
Monkey embryonic stem (ES) cell is a useful tool for preclinical studies of regenerative medicine. In this paper, we investigated whether monkey ES cells can be differentiated into osteoblasts in vitro using factors known to promote osteogenesis. We prepared embryoid bodies (EB) in the presence of retinoic acid (RA) and subsequently differentiated in the(More)
The dietary components responsible for the development of Barrett's esophagus (BE) and esophageal adenocarcinoma (EAC) remain unclear. Wistar rats were divided into four groups based on their diet: a low soybean-oil diet, a low cow-fat diet, a high soybean-oil diet, and a high cow-fat diet. First, we evaluated the bile acid composition of the bile juice in(More)
Several epidemiological cohort studies have suggested that duodeno-gastroesophageal reflux per se induces Barrett's esophagus leading to increased risk of the development of esophageal adenocarcinoma (EAC). However, the exact causative factors behind EAC remain unclear. Recently, we designed a new duodenal contents reflux model which retained normal stomach(More)
Laser diffraction (LD) has been recognized as a method for estimating particle size distribution. Here, a recently developed quantitative LD (qLD) system, which is an LD method with extensive deconvolution analysis, was employed for the quantitative assessment of protein particles sizes, especially aimed at the quantification of 0.2-10 μm diameter(More)
Two-pore domain K+ channels are widely expressed in many types of cells, and have various important functions, especially maintaining the resting membrane potential. In the previous report, we have confirmed the presence of several kinds of two-pore domain K+ channels in the periodontal ligament (PDL) fibroblasts. It is well known that dexamethasone (Dex)(More)