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Multi-agent systems can be viewed as systems in which large numbers of agents process jobs by interacting with each other. We have been applying such a multi-agent system to electronic commerce (EC) on the Internet since December 1997. Since the server on the system has to host thousands of agents that process jobs in a disorderly manner, the mechanism for(More)
There are many studies on ABS and several frameworks for ABS have already been published. However, there are few frameworks that can enable agent-based simulation using large numbers of agents. We have been developing a Java-based platform for Massive Agent-Based Simulation (MABS) called "Zillions of Agents-based Simulation Environment" or ZASE. The purpose(More)
Recently Web sites have been providing users with services in accordance with their preference data. In addition to such configuration services, notification services, which process jobs in response to events which occurred at a server in the users' absence, and asynchronous services, which perform jobs after users submit requests, are also available. An(More)
BACKGROUND Ezrin is a member of the ezrin, radixin, and moesin family that provides a functional link between the plasma membrane and the cortical actin cytoskeleton. A correlation between ezrin overexpression and aggressive cancer behavior has been recently reported in various tumor types. However, its roles in the mechanisms underlying progression of(More)
p62/SQSTM1 (sequestosome1) has never been evaluated in oral epithelium. In order to clarify the role of p62/SQSTM1 in carcinogenesis in oral epithelium, both p62/SQSTM1 and Nrf2 were immunohistochemically evaluated in 54 carcinomas and 14 low grade dysplasias. p62/SQSTM1 knockdowns were also designed in oral cancer cells, and we analyzed the Nrf2 pathway,(More)
In this paper, we describe technologies for an agent server capable of hosting tens of thousands of agents. The agent server needs a thread management mechanism, a memory management mechanism, and a recovery management mechanism. We have developed a framework and agent running environment named Caribbean. We describe the application scenario and the(More)