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BACKGROUND Late stent thrombosis (LST) after Cypher and Taxus drug-eluting stent placement has emerged as a major concern. Although the clinical predictors of LST have been reported, specific morphological and histological correlates of LST remain unknown. METHODS AND RESULTS From a registry totaling 81 human autopsies of drug-eluting stents, 46 (62(More)
OBJECTIVES Human coronary bare-metal stents (BMS) and drug-eluting stents (DES) from autopsy cases with implant duration >30 days were examined for the presence of neointimal atherosclerotic disease. BACKGROUND Neointimal atherosclerotic change (neoatherosclerosis) after BMS implantation is rarely reported and usually occurs beyond 5 years. The incidence(More)
OBJECTIVES We investigated the frequency of the noncardiac findings in cardiac imaging with multidetector computed tomography (MDCT). BACKGROUND Multidetector computed tomography is an accepted new tool to evaluate the heart. In cardiac MDCT scans, organs other than the heart are also irradiated, but usually not assessed. METHODS A total of 503 patients(More)
BACKGROUND Stent fracture is one of the possible causes of restenosis after sirolimus-eluting stents (SES) implantation. The aim of our study was to evaluate the prevalence and clinical impact of coronary stent fracture after SES implantation. METHODS From our prospective institutional database, 280 patients were treated solely with SES from August 2004(More)
BACKGROUND The long-term safety of drug-eluting stents (DES) for acute myocardial infarction (AMI) remains uncertain. Using autopsy data, we evaluated the pathological responses of the stented segment in patients treated with DES for AMI and compared with patients with stable angina. METHODS AND RESULTS From the CVPath Registry of 138 DES autopsies, we(More)
OBJECTIVES Using human pathologic specimens from the CVPath registry, we aimed to investigate the location of the atherosclerotic plaque at bifurcation in native coronary atherosclerotic lesions and to determine the responses at bifurcation after implantation of bare-metal stents (BMS) and drug-eluting stents (DES). BACKGROUND Greater atherosclerotic(More)
BACKGROUND It has been reported that multidetector spiral computed tomography (MDCT) allows the classification of coronary plaques by measuring computed tomography (CT) density values. However, the impact of CT density values in culprit lesions on the occurrence of transient no-reflow during percutaneous coronary intervention (PCI) has not been(More)
OBJECTIVES The aim of this study was to perform pathologic assessment on stent fracture. BACKGROUND Clinically, stent fracture has been reported in 1% to 2% of patients after drug-eluting stent (DES) implantation. METHODS High-contrast film-based radiographs of 177 consecutive lesions from the CVPath DES autopsy registry were reviewed. Stent fracture(More)
OBJECTIVE To characterize various dysgraphic symptoms in parietal agraphia. METHOD We examined the writing impairments of four dysgraphia patients from parietal lobe lesions using a special writing test with 100 character kanji (Japanese morphograms) and their kana (Japanese phonetic writing) transcriptions, and related the test performance to a lesion(More)
BACKGROUND Percutaneous coronary intervention for hemodialysis patients has been hampered by the high rate of adverse cardiac events. Our aim was to investigate whether sirolimus-eluting stents (SESs) improve clinical outcomes of hemodialysis patients compared with bare-metal stents (BMSs). STUDY DESIGN Retrospective study. SETTING & PARTICIPANTS 123(More)