Gail S. Bazzano

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A study was conducted at Charity Hospital, New Orleans, among 272 adolescent pregnant women to ascertain the relationship of pregnancy outcome to plasma zinc level measured once at the time of enrollment. Regression analyses were performed on zinc status versus parameters concerning success of pregnancy corrected for gestational stage at specimen(More)
It has been demonstrated that topical application of all-trans retinoic acid and other retinoids can alter the hair-growth cycle in the C3H mouse model. The anagen phase is prolonged and the telogen phase is shortened. This effect is similar to the effect of minoxidil on the hair-cycle dynamics in this animal model. The levels of cellular retinoic acid(More)
Although the mechanisms of follicular regression in androgenetic alopecia are not fully understood, retinoids may be important in changing the status of regressing follicles. There are many reports documenting reversal of epithelial dysplastic changes with retinoids. Although none of the studies with retinoids have concentrated on the precise mechanisms of(More)
The effect of cholesterol supplementation on the hypocholesterolemia induced by glutamic acid feeding has been studied in the Mongolian gerbil. Serum triglycerides and phospholipids and hepatic cholesterol and triglyceride contents have also been studied during the control and glutamate feeding. Cholesterol supplementation (0.05% and 1.0%) did not diminish(More)
Cellular retinoic acid-binding protein levels were determined in the skin and testes of normal and retinol-deficient rats. All-trans [3H]retinoic acid (1.1 TBq/mmol) was used to titrate the specific binding sites in tissue cytosol preparations. Scatchard plot analyses were used to determine the concentration of cellular retinoic acid-binding protein and its(More)
In order to study the metabolism of 13-cis-retinoic acid (13-cis-RA) in animal sebaceous glands and analogues, preputial glands from normal and vitamin A-deficient male rats were incubated with [3H]13-cis-RA for up to 24 h; vitamin A-normal hamster costovertebral glands (flank organs) were incubated for 24 h as well. High-performance liquid chromatography(More)
Topical all-trans-retinoic acid (tretinoin) alone and in combination with 0.5% minoxidil has been tested for the promotion of hair growth in 56 subjects with androgenetic alopecia. After 1 year, the combination of topical tretinoin with 0.5% minoxidil resulted in terminal hair regrowth in 66% of the subjects studied. Tretinoin was shown to stimulate some(More)
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