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  • Ian Rylance Booth, Gail P. Ferguson, Simon Miller, Chiang-Shan Li, Banuri Gunasekera, Seonag Kinghorn
  • Medicine, Biology
  • Biochemical Society transactions
  • 2003 (First Publication: 1 December 2003)
  • The production of MG (methylglyoxal) in bacterial cells must be maintained in balance with the capacity for detoxification and protection against this electrophile. Excessive production of MG leadsExpand
  • Gail P. Ferguson, A. K. Datta, John Baumgartner, Roy Martin Roop, Russ W Carlson, Graham C Walker
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2004 (First Publication: 6 April 2004)
  • Sinorhizobium meliloti, a legume symbiont, and Brucella abortus, a phylogenetically related mammalian pathogen, both require the bacterial-encoded BacA protein to establish chronic intracellularExpand
  • Gail P. Ferguson, Debra McLaggan, Ian Rylance Booth
  • Medicine, Biology
  • Molecular microbiology
  • 1995 (First Publication: 15 September 1995)
  • Escherichia coli possesses two glutathione-gated potassium channels, KefB and KefC, that are activated by glutathione-S-conjugates formed with methylglyoxal. We demonstrate that activation of theExpand
  • Morag J MacLean, L. S. Ness, Gail P. Ferguson, Ian Rylance Booth
  • Medicine, Biology
  • Molecular microbiology
  • 1998 (First Publication: 1 February 1998)
  • The glyoxalase I gene (gloA) of Escherichia coli has been cloned and used to create a null mutant. Cells overexpressing glyoxalase I exhibit enhanced tolerance of methylglyoxal (MG) and exhibitExpand