Gail Caskey Winkler

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Lungs of newborn and of 7- and 30-day-old pigs were fixed at total capacity by a standardized procedure. Stereologic morphometry was applied to random ultrathin sections of parenchyma. Relative volume density, absolute volume, and capillary surface coverage of intravascular macrophages as well as parameters of relative morphometric diffusion capacity of(More)
Ultrastructural studies of near-term to 2-month-old pigs were done to document characteristics and developmental changes of intravascular macrophages in pulmonary capillaries. Evidence is presented that blood monocytes colonize the porcine lung perinatally, replicate within capillaries postnatally, and attach to endothelium by intercellular junctions during(More)
Morphology and postnatal development of the porcine lung are described in animals ranging in age from newborn through 60 days. Standardized fixation was accomplished by intratracheal instillation of glutaraldehyde under constant pressure. Light microscopic, scanning, and transmission electron microscopic investigations revealed that the porcine lung follows(More)
Alveolar regions of normal pig lungs (newborn to 60-day-old) were characterized morphometrically to provide a basis for comparison in future investigations of porcine respiratory diseases. Endotracheal installation of fixative was done to expand the lungs uniformly at total capacity. Differential effects of lobar variations were determined by stratified(More)
Serum samples from 1421 domestic cats (561 healthy, 860 sick) were tested for FIV-, FeLV- and coronavirus infection. The results were stored in a computer data base and compared with epidemiologic data and clinical findings. All 3 infections were significantly more prevalent in sick than healthy cats: FIV was found in 0.7% of healthy and 3.4% of sick cats.(More)
Mice were injected intraperitoneally with either amosite, crocidolite or chrysotile. Tissue specimens of the mesentery (appendices epiploicae) were taken after 2 h, 24 h and 7 days and prepared for scanning electron microscopy. Subsequent examination revealed numerous fibers penetrating the mesothelium. The penetration is regarded as the earliest(More)