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The total plasma concentration of homocysteine is a marker of this amino acid's atherogenic potential. However, the homocysteine pool exists almost entirely as oxidized homocysteine equivalents (OHcyE), composed of homocystine and cysteine-homocysteine disulphides (20-30%), and protein-bound disulphide (70-80%). We have noticed that the total concentration… (More)
In a study on the prevalence of cardiovascular autonomic neuropathy and retinopathy in a group of 57 diabetic subjects, an increased prevalence of these complications related to the duration of diabetes has been found.