• Citations Per Year
Learn More
Human beings, like other living organisms, have physiologic systems that are cyclic in nature. Many of these systems have a circadian length. This provides for internal stability while at the same time enabling the organism to interact with the external environment and respond to changes in that environment. These physiologic systems, including those with a(More)
The following factors must be considered when determining the need for theophylline and diphenylhydantoin (DPH) levels: accuracy and reproducibility, turnaround time, and cost-benefit ratio for the patient. Serum levels must bear a relationship to the therapeutic effects of the drugs. In addition, the pharmacology of the drugs must be of such an order of(More)
A 50-year-old man presented to the emergency department in a coma with fixed and dilated pupils. Skin and mucous membranes were noted to be an ashen grey color. Initial vital signs were blood pressure of 104/70 mm Hg; pulse, 110; and respirations, 12. Initial arterial blood gases were pH of 7.25; PaCO2, 26.6 mm Hg; PaO2, 22.1 mm Hg; oxygen saturation,(More)
Pudendal neuropathy is common. The diagnosis is clinical and the confirmation is electrophysiological. Distal pudendal nerve latencies have been used but they are unspecific and do not allow to localize the site of compression. A preliminary electrophysiological study has suggested separate innervations of the anterior and the posterior anal sphincter(More)
STUDY OBJECTIVE To determine antibody titers to hepatitis B surface antigen (anti-HBsAg) among previously vaccinated emergency physicians and to assess the degree of compliance with Centers for Disease Control and Prevention (CDC) postvaccination guidelines. METHODS A descriptive analysis was performed of anti-HBsAg titer determinations and vaccination(More)
The follow-up of a cohort of 528 model makers and a control group of 2273 tool makers shows an unusual pattern of mortality in the model makers' cohort. In contrast to the usual ranking, malignant neoplasms are the most frequent group of cause of death followed by diseases of the cardiovascular system. The rate ratio (RR) for malignant tumors is(More)
An historical follow-up study of 528 model makers in a German automobile company found an unusual pattern of mortality among these workers that included an increased risk of total cancer and tumors of the stomach, genitourinary organs, and the brain (Becker et al, 1992). Because of small numbers of cases and problems with the validity of causes of death, we(More)