Gabriele Tuchscherer

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The study of conformational transitions of peptides has obtained considerable attention recently because of their importance as a molecular key event in a variety of degenerative diseases. However, the study of peptide self-assembly into beta-sheets and amyloid beta (Abeta) fibrils is strongly hampered by their difficult synthetic access and low solubility.(More)
pour toute l'aide et le soutien qu'il a m'apportés durant cette thèse. Je souhaite remercier tous les membres du groupe Mutter et plus particulièrement, Mandal, Abstract The rapid growing number of patients diagnosed with a neurodegenerative disease and more particularly with Alzheimer's disease (AD) has stimulated intensive research in determining and(More)
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