Gabriele Ferraris

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The signs that may arise after perinatal infection with human immunodeficiency virus type 1 (HIV-1) have been classified by the Centers for Disease Control, but the clinical usefulness of the classification system and the prognostic importance of each disease pattern have not been established. We sought to address these issues by analysing data from the(More)
To estimate the risk of mother-to-child transmission of hepatitis C virus (HCV) and identify correlates of transmission, 245 perinatally exposed singleton children followed prospectively beyond 18 months of age were studied. Overall, 28 (11.4%) of the 245 children acquired HCV infection. Transmission occurred in 3 of 80 children (3.7%) whose mothers had HCV(More)
Diagnosis of perinatal HIV-1 infection is complicated by the persistence of maternal antibodies and the conflicting reports on polymerase chain reaction (PCR) reactivity in children born to HIV-1-seropositive mothers. We have compared PCR with other diagnostic methods for perinatal HIV-1 infection and have attempted also to identify maternal markers which(More)
OBJECTIVE To analyze determinants of pregnancy outcome, among HIV infected and uninfected intravenous drug users. STUDY DESIGN A total of 315 pregnant current intravenous drug users, IVDU (151 HIV infected and 164 HIV uninfected subjects) were referred to the Center for Pregnant Drug Addicts of the Mangiagalli Clinic, Milan, Italy, for internatal care and(More)
BACKGROUND In recent years, combination antiretroviral therapy has substantially improved the prognosis of human immunodeficiency virus type-1 (HIV-1) infection. However, at present, information regarding the effects of these regimens during pregnancy is limited. METHODS Side-effects, vertical transmission rate and neonatal outcome associated with(More)
402 radical hysterectomies (17 ultraradical) were performed with lymphadenectomy. Positive metastatic nodes (N+) rate was 23.6% with an arithmetic mean of 22 excised lymph nodes. Single N+ belonged mostly to the obturatory group, double N+ to obturatory and external iliac groups, while multiple N+ (24 cases) had no particular site. Neoplastic invasion,(More)
A clinical assessment of gestational age was performed in a group of 92 newborn infants. The Dubowitz method (1970) based on 10 neurological and 11 "external" criteria and the Finnström method (1977) based on 7 "external" criteria have been applied. A comparison between these two methods showed a correct estimation of gestational age within +/- 2 weeks in(More)
BACKGROUND There is currently an experts' agreement discouraging interruption of antiretroviral treatment (ART) during the first trimester of pregnancy in women infected with human immunodeficiency virus type 1 (HIV-1). However, this recommendation is poorly supported by data. We evaluated the effects of discontinuing ART during pregnancy on the rate of(More)
Ten patients suffering from progressive systemic sclerosis, who responded poorly to conventional therapy, underwent plasma exchange (PE) therapy in conjunction with drug therapy. The frequency of PE was twice weekly for 4-6 weeks, two or three times per year, with a summer interruption, when in our own experience a spontaneous relief of symptoms occurs. To(More)