Gabriele Candiani

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BACKGROUND A promising strategy to create stimuli-responsive gene delivery systems is to exploit the redox gradient between the oxidizing extracellular milieu and the reducing cytoplasm in order to disassemble DNA/cationic lipid complexes (lipoplexes). On these premises, we previously described the synthesis of SS14 redox-sensitive gemini surfactant for(More)
The successful launch of MERIS in March 2002 has given a great opportunity to understand the changes of water colour with high temporal and spatial resolutions. In this study, potentials of MERIS sensor were investigated to describe variations of optically active substances of Lake Garda. The basin is located in the Italian sub-alpine lacustrine district,(More)
We present an integrated experimental-computational mechanobiology model of chondrogenesis. The response of human articular chondrocytes to culture medium perfusion, versus perfusion associated with cyclic pressurisation, versus non-perfused culture, was compared in a pellet culture model, and multiphysic computation was used to quantify oxygen transport(More)
High-spatial-resolution satellites usually have the constraint of a low temporal frequency, which leads to long periods without information in cloudy areas. Furthermore, low-spatial-resolution satellites have higher revisit cycles. Combining information from high-and low-spatial-resolution satellites is thought a key factor for studies that require dense(More)
Rangeland monitoring services require the capability to investigate vegetation condition and to assess biomass production, especially in areas where local livelihood depends on rangeland status. Remote sensing solutions are strongly recommended, where the systematic acquisition of field data is not feasible and does not guarantee properly describing the(More)
BACKGROUND Successful non-viral gene delivery currently requires compromises to achieve useful transfection levels while minimizing toxicity. Despite high molecular weight (MW) branched polyethylenimine (bPEI) is considered the gold standard polymeric transfectant, it suffers from high cytotoxicity. Inversely, its low MW counterpart is less toxic and(More)
This study is part of ongoing research efforts aimed to developing Earth Observation (EO) strategies towards the implementation of the Water Framework Directive (WFD), ensuring systematic monitoring of water quality in the largest lakes of the Subalpine ecoregion (northern Italy). To t he aim the Medium Resolution Imaging Spectrometer (MERIS) Full(More)
This paper describes the use of airborne hyperspectral remote sensing for mapping asbestos roofs in an orographic complex area in Northern Italy, the Aosta Valley. Using training samples collected during field surveys, thematic classification was able to detect the majority of asbestos surfaces. Considering the total amount of asbestos areas validation(More)
This study shows a comparison between pixel-based and object-based approaches in data fusion of high-resolution multispectral GeoEye-1 imagery and high-resolution COSMO-SkyMed SAR data for land-cover/land-use classification. The per-pixel method consisted of a maximum likelihood classification of fused data based on discrete wavelet transform and a(More)