Deficiency in tuberin results in activation the mTOR pathway and leads to accumulation of cell matrix proteins. The mechanisms by which tuberin regulates fibrosis in kidney angiomyolipomas (AMLs) of tuberous sclerosis patients are not fully known. In the present study, we investigated the potential role of tuberin/mTOR pathway in the regulation of cell… (More)
This paper proposes a comprehensive framework for the accuracy assessment of taxonomically diverse LULC maps. A widely accepted difficulty in assessing such maps is associated with the vagueness in the interpretation of complex landscapes. For every class of the map, this method quantified the thematic and positional fuzziness of accuracy, induced by this… (More)
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This study identifies drivers of deforestation in Mexico by applying Geographically Weighted Regression (GWR) models to cartographic and statistical data. A wall-to-wall multitemporal GIS database was constructed incorporating digital land use/land cover maps for 2002 and 2007; along with ancillary data (road network, settlements, topography and… (More)