Gabriel Silberman

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OBJECTIVE Breast cancer remains the highest incident cancer among females in the United States and previous research suggests that a considerable portion of patients will eventually progress to the metastatic phase of the disease. This paper provides the first estimate of the lifetime direct costs of treating metastatic disease for one annual diagnostic(More)
BACKGROUND Allogeneic bone marrow transplantation, a sophisticated and expensive procedure, is the only curative therapy for chronic myeloid leukemia (CML). We examined the availability and appropriateness of allogeneic bone marrow transplantation for CML in 10 economically advanced countries with diverse health care systems. For each country we obtained(More)
Cross-design synthesis is a new (and still evolving) strategy for providing quantitative results that capture the strengths and minimize the weaknesses of different kinds of research. The strategy, which is being developed to answer questions about the effects of treatment in medical practice, includes (a) identifying complementary research designs and(More)
OBJECTIVES In this study, cancer survival rates for patients diagnosed in Ontario and selected areas within the United States were compared. METHODS Relative survival rates were computed for patients aged 15 through 84 years diagnosed with any of four forms of cancer (breast, colon, lung, and Hodgkin's disease). The cohorts represented those diagnosed(More)
The lessons of these examples are clear. If physicians will not decide on how to decide, others will. This theme replicates that expressed in the discussion of cost. Oncologists charged with providing palliative cancer care are in a field rife with growing tensions imposed by increasing demands for therapy. If the profession does not develop a strategy for(More)