Gabriel Marie Ranjalahy

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SETTING A national survey of Mycobacterium tuberculosis resistance was conducted for the first time in Madagascar between October 2005 and July 2007. OBJECTIVE To determine resistance rates among new and previously treated cases of pulmonary tuberculosis. METHODS In a cluster sampling representative of the general population of the country, 1275(More)
Tuberculosis (TB) is a bacterial disease caused by organisms of the Mycobacterium tuberculosis complex (MTC). The definitive diagnosis of TB depends on the isolation and identification of the etiologic agent. Clinical identification of mycobacteria remains difficult and time-consuming. Cultures in specific media can result not only in M. tuberculosis (MTB)(More)
BACKGROUND By 2005, Madagascar had not achieved its goal of eliminating leprosy. During reexamination of leprosy patients, rates of diagnostic error ranged from 4.5 to 62%, casting doubt on the reported prevalence of leprosy. We therefore decided to carry out a survey of the quality of leprosy diagnosis. PATIENTS AND METHODS The survey consisted in(More)
The performance of the immunochromatographic assay, SD BIOLINE TB Ag MPT64 RAPID®, was evaluated in Madagascar. Using mouse anti-MPT64 monoclonal antibodies for rapid discrimination between the Mycobacterium tuberculosis complex and nontuberculous mycobacteria, the kit was tested on mycobacteria and other pathogens using conventional methods as the gold(More)
BACKGROUND To improve the diagnosis of tuberculosis (TB), more rapid diagnostic techniques such as antibody detection based on immunochromatographic methods were developed. The objective of this study was to evaluate the performance of the SD Rapid TB kit for the diagnosis of active TB with serums from patients and close contact controls in Antananarivo,(More)
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