Gabriel Kacso

Ioan Stefan Florian2
Lucian Craciun2
Mihaela Aldea2
Sanda Boca1
2Ioan Stefan Florian
2Lucian Craciun
2Mihaela Aldea
1Sanda Boca
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  • Mihaela Aldea, Lucian Craciun, Ciprian Tomuleasa, Ioana Berindan-Neagoe, Gabriel Kacso, Ioan Stefan Florian +1 other
  • 2014
After sitting many years on the shelves of drug stores as a harmless antidiabetic drug, metformin comes back in the spotlight of the scientific community as a surprisingly effective antineoplastic drug. Metformin targets multiple pathways that play pivotal roles in cancer progression, impacting various cellular processes, such as proliferation, cell death,(More)
Extensive hypoxic regions are the daunting hallmark of glioblastoma, as they host aggressive stem-like cells, hinder drug delivery and shield cancer cells from the effects of radiotherapy. Nanotechnology could address most of these issues, as it employs nanoparticles (NPs) carrying drugs that selectively accumulate and achieve controlled drug release in(More)
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