Gabriel J. Hauser

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To evaluate the relationship between postoperative serum lactate levels and outcome in children undergoing open heart surgery. Prospective, noninterventional study. Pediatric intensive care unit (PICU) of a university hospital. 41 nonconsecutive children who had had cardiopulmonary bypass for repair of congenital heart disease. None. Serum lactate levels(More)
OBJECTIVE To compare the effects of administering propofol as a continuous infusion vs. bolus dosing in children undergoing ambulatory oncologic procedures in the pediatric intensive care unit (PICU). DESIGN Prospective, randomized study. SETTING Tertiary PICU in a university hospital. PATIENTS Ambulatory oncology patients scheduled for diagnostic or(More)
OBJECTIVES To study the hypothesis that endotoxin and tumor necrosis factor-alpha (TNF) are released into the circulation during the perioperative period in children undergoing open-heart surgery, and to assess the possible role of these factors in postoperative morbidity. DESIGN Prospective study. SETTING Operating room and ICU of a children's(More)
Neuropeptide Y (NPY), a sympathetic and platelet-derived vasoconstrictor, acts both directly and by potentiating adrenergic responsiveness and therefore may be beneficial in endotoxic shock, where suppressed vascular responsiveness to adrenergic agents is a key factor. This was studied in anesthetized rats. First, infusion of a nonhypotensive dose of(More)
Endotoxin (lipopolysaccharide, LPS)-induced hypotension is, in part, mediated via induction of nitric oxide synthase (iNOS), release of nitric oxide, and suppression of vascular reactivity (vasoplegia). Induction of heat shock proteins (HSP) or inhibition of iNOS expression improves survival in LPS-challenged rodents. We studied the effect of induction of(More)
Objective: To evaluate the relationship of perioperative levels of interleukin 6 (IL-6) in serum and bronchoalveolar fluid with morbidity and mortality in children undergoing cardiopulmonary bypass (CPB). Design: Prospective, noninterventional study. Setting: Operating room and pediatric intensive care unit (PICU) of a university hospital. Interventions:(More)
During the period between October 1984 and January 1985, an outbreak of Serratia marcescens took place in the Serlin Maternity Hospital in Tel-Aviv. Four major and six minor infections were noted in newborn and preterm infants. An additional group of 24 neonates were asymptomatic carriers of S. marcescens. Extensive control measures were undertaken,(More)
The ability of lymphocytes from a patient suffering from the acquired immune deficiency syndrome (AIDS) to produce interleukin-2 (IL-2) was found to be comparable to that of his healthy sex partner and to that of a normal control. Addition of exogenous IL-2 to lymphocyte cultures did not improve the poor mitogen response to phytohaemagglutinin in this(More)
OBJECTIVES To evaluate our experience with propofol anesthesia delivered by pediatric intensivists in the pediatric intensive care unit (PICU) to facilitate elective oncology procedures in children performed by pediatric oncologists. METHODS Elective oncology procedures performed with propofol anesthesia in our multidisciplinary, university-affiliated(More)