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Leptin has beneficial effects on glucose metabolism via actions in the hypothalamus, but the roles of specific subgroups of neurons responsible for these antidiabetic effects remain unresolved. We generated diabetic Lep(ob/ob) or Lepr(db/db) mice lacking or re-expressing leptin receptors (LepRb) in subgroups of neurons to explore their contributions to(More)
This article shows the improving of analysis patterns in the geographic domain through ontological meta-properties, where each pattern's class has its concept analyzed ontologically. This improvement also permits to restructure the class diagram of analysis patterns, increasing the reuse quality. Besides improving the analysis patterns, it is proposed one(More)
Research examining the sexual behaviors and experiences of behaviorally bisexual men is limited. Most studies focus primarily on highlighting sexual risk behaviors among groups of "men who have sex with men (MSM)" or "gay and bisexual men," which may not be appropriate in terms of behaviorally bisexual men's sexual repertoires with both men and women. This(More)
In recent decades there has been an increase in interest on methods for the automatic construction of distributional thesauri from corpora. Efforts to systematically evaluate and improve the resulting thesauri have been made for languages like English and French, but for Portuguese there is an urgent need for such initiatives. This paper presents a(More)
OBJECTIVE Hypothalamic agouti-related peptide (AgRP) and pro-opiomelanocortin (POMC) expressing neurons play critical roles in control of energy balance. Glutamatergic input via n-methyl-d-aspartate receptors (NMDARs) is pivotal for regulation of neuronal activity and is required in AgRP neurons for normal body weight homeostasis. NMDARs typically consist(More)
Although frequently cited as being at high risk for HIV/STI transmission, little is known about behaviorally bisexual men's patterns and experiences of condom use and nonuse with male and female sexual partners. Using a variety of recruitment techniques informed by a Community Advisory Committee, a total of 77 behaviorally bisexual men were recruited from(More)
Studies concerning behaviorally bisexual men continue to focus on understanding sexual risk in according to a narrow range of sexual behaviors. Few studies have explored the subjective meanings and experiences related to bisexual men's sexual behaviors with both male and female partners. In-depth, semi-structured interviews were conducted with 75 men who(More)
This paper presents an ongoing work on ontology learning from text, focusing on the acquisition of concepts and relations. In order to do that, this work investigates approaches for ontology learning, and presents a proposal based on graphs metrics to identify concepts, and text analysis to find relations between the concepts. processamento dessas(More)
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