Gabriel Gastaminza

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BACKGROUND Desensitization has been used for some decades to treat patients with the allergenic drug when an alternative drug with similar efficacy and safety is not available. We present the results from a series of oncology patients desensitized at our hospital during the last 2 years. OBJECTIVE To assess the efficacy of a new desensitization protocol(More)
BACKGROUND Natural rubber latex allergy is a common and unsolved health problem. Since the avoidance of exposure is very difficult, immunotherapy is strongly recommended, but before its use in patients, it is essential to prove the efficacy and safety of extracts.The aim of the present randomised, double-blind, placebo-controlled clinical trial was to(More)
BACKGROUND Several studies have identified neuromuscular blocking agents as the most common cause of anaphylaxis during general anesthesia. The reported frequencies vary considerably between countries. There are few reports from Spain, probably due to the low prevalence of reactions. METHODS For 5 years (1998-2002), all the patients who presented(More)
The purpose of this investigation was to compare the genotypic profiles of Staphylococcus aureus isolated from atopic dermatitis (AD) patients and from control subjects, and to study the relationship between clinical severity, immune response, and genomic pattern of S. aureus isolated from AD patients. We selected 32 patients with AD and S. aureus skin(More)
Strictly speaking, biological drugs are defined as drugs obtained using biotechnology that act on the immune system. They encompass monoclonal antibodies, fusion proteins, and cytokines. Although they are restricted to specific diseases, they have been increasingly used in recent years, with the consequent reporting of adverse reactions, many of which occur(More)
Cold urticaria is one of the least common types of urticaria, affecting approximately 1% to 3% of all patients with urticaria [1]. Patients present generalized or local wheal lesions in areas that come into contact with cold stimuli such as cold air, water, or objects. The symptoms may or may not be accompanied by angioedema. Cold urticaria can be primary(More)
Key words: IFN-a. Delayed hypersensitivity reactions. Amoxicillin. In vitro test. Palabras clave: IFN-a. Reacciones retardadas de hipersensibilidad. Amoxicilina. Tests in vitro. In recent years many studies have investigated the production of cytokines in the supernatants of cell cultures from patients with delayed hypersensitivity reactions to drugs as an(More)
Serious complications can occur during the study of patients who develop allergic reactions while under treatment with multiple drugs. In such cases, it is necessary to conduct an exhaustive investigation of the drugs involved and comprehensive allergy tests with assessment of immediate and late reactions. We present the cases of 2 patients that developed a(More)
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