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  • Elizabeth K. Day, Beatrice Waters, +5 authors Gabor Jarai
  • Chemistry, Medicine
  • European journal of pharmacology
  • 2008 (First Publication: 1 December 2008)
  • Imatinib, nilotinib and dasatinib are protein kinase inhibitors which target the tyrosine kinase activity of the Breakpoint Cluster Region-Abelson kinase (BCR-ABL) and are used to treat chronicContinue Reading
  • Carol E. Jones, Suzanne Holden, +10 authors Peter M. Finan
  • Medicine, Biology
  • Molecular pharmacology
  • 2003 (First Publication: 1 March 2003)
  • Using a bioinformatics approach, we have isolated a novel G-protein-coupled receptor (GPCR), R527, and have demonstrated that this receptor shows no significant homology to previously deorphanizedContinue Reading
  • Shida Yousefi, Paul R Cooper, Sharon Lee Potter, Bengt Mueck, Gabor Jarai
  • Biology, Medicine
  • Journal of leukocyte biology
  • 2001 (First Publication: 1 June 2001)
  • The migration of neutrophils into sites of acute and chronic inflammation is mediated by chemokines. We used degenerate-primer reverse transcriptase-polymerase chain reaction (RT-PCR) to analyzeContinue Reading
  • Yosuke Matsuno, Ana Lucia Coelho, Gabor Jarai, John Westwick, Cory M. Hogaboam
  • Biology, Medicine
  • The international journal of biochemistry & cell…
  • 2012 (First Publication: 1 May 2012)
  • Epithelial-mesenchymal transition (EMT) is a process by which epithelial cells undergo phenotypic transition to mesenchymal cells and thus is involved in the pathogenesis of tumor metastasis andContinue Reading
  • Victoria J. Burton, Alan M. Holmes, +5 authors David C. Budd
  • Medicine
  • Blood
  • 2011 (First Publication: 27 October 2011)
  • Previous studies from our group have demonstrated that bone morphogenetic protein receptor-II (BMPR-II), expressed on pulmonary artery endothelial cells, imparts profound anti-inflammatory effects byContinue Reading