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C-arm fluoroscopy is ubiquitous in contemporary surgery, but it lacks the ability to accurately reconstruct three-dimensional (3D) information. A major obstacle in fluoroscopic reconstruction is discerning the pose of the x-ray image, in 3D space. Optical/magnetic trackers tend to be prohibitively expensive, intrusive and cumbersome in many applications. We(More)
Introduction: MRI provides excellent soft-tissue contrast and promises to improve image-guided prostate interventions, presently performed with ultrasound [1,2]. MRI-guided transperineal prostate biopsy has been demonstrated inside an open MRI scanner [3]. Transrectal prostate biopsy has been demonstrated inside a high-field MR scanner utilizing passive(More)
BACKGROUND With increasing research on system integration for image-guided therapy (IGT), there has been a strong demand for standardized communication among devices and software to share data such as target positions, images and device status. METHOD We propose a new, open, simple and extensible network communication protocol for IGT, named OpenIGTLink,(More)
A methodology is presented for constructing a statistical atlas of spatial distribution of prostate cancer from a large patient cohort, and it is used for optimizing needle biopsy. An adaptive-focus deformable model is used for the spatial normalization and registration of 100 prostate histological samples, which were provided by the Center for Prostate(More)
Intraoperative dosimetric quality assurance in prostate brachytherapy critically depends on discerning the three-dimensional (3D) locations of implanted seeds. The ability to reconstruct the implanted seeds intraoperatively will allow us to make immediate provisions for dosimetric deviations from the optimal implant plan. A method for seed reconstruction(More)
Extracting the prostate from magnetic resonance (MR) imagery is a challenging and important task for medical image analysis and surgical planning. We present in this work a unified shape-based framework to extract the prostate from MR prostate imagery. In many cases, shape-based segmentation is a two-part problem. First, one must properly align a set of(More)
—Segmentation of bone surface in ultrasound images has numerous applications in computer aided orthopedic surgery. A robust bone surface extraction technique for ultrasound images can be used to non-invasively probe the bone surface. In this work, we present early results with an intuitive and compu-tationally inexpensive bone segmentation approach. The(More)
We developed a robot system that can be used for image-guided experimental procedures on small animals, where the goal is to perform physical actions at specific positions identified on a preoperative image. The animal is first placed in a fixture that is compatible with all imaging systems of interest, including PET, SPECT, CT and MRI. After imaging, the(More)
Conventional freehand 3D ultrasound (US) is a complex process, involving calibration, scanning, processing, volume reconstruction, and visualization. Prior to calibration, a position sensor is attached to the probe for tagging each image with its position and orientation in space; then calibration process is performed to determine the spatial transformation(More)