Gaëlle Boncompain

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Reactive oxygen species (ROS) are many-faceted compounds involved in cell defense against pathogens, as well as in cell signaling. Their involvement in the response to infection in epithelial cells remains poorly documented. Here, we investigated the production of ROS during infection with Chlamydia trachomatis, a strict intracellular pathogen, in HeLa(More)
Shigella infection causes destruction of the human colonic epithelial barrier. The Golgi network and recycling endosomes are essential for maintaining epithelial barrier function. Here we show that Shigella epithelial invasion induces fragmentation of the Golgi complex with consequent inhibition of both secretion and retrograde transport in the infected(More)
INSERM; U950; Membrane Traffic in Health and Disease; Paris, France; Univ Paris Diderot; Sorbonne Paris Cit e; ERL U950; Paris, France; CNRS; UMR 7592; Institut Jacques Monod; Paris, France; State Key Laboratory of Molecular Developmental Biology; Institute of Genetics and Developmental Biology; Chinese Academy of Sciences; Beijing, China; Institut Curie;(More)
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