Gaël Boivin

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The pharmacokinetics of ciprofloxacin and its metabolite 1 (desethyleneciprofloxacin) were studied in 17 obese men (mean age, 29.2 +/- 7.5 years; mean weight, 110.7 +/- 20.2 kg; mean body mass index, 36.4 +/- 3.9 kg/m2) and 11 control subjects (men of normal weight; mean age, 25.0 +/- 5.1 years; mean weight, 71.8 +/- 9.9 kg; mean body mass index, 23.3 +/-(More)
40 patients undergoing middle ear microsurgery were anaesthetized with a narconeuroleptanalgesia (droperidol, phenoperidine, thiopentone) associated with a randomly selected halogenated volatile anaesthetic, either halothane or isoflurane at a concentration of 1 MAC. Clinical and haemodynamic tolerance was perfect. Respiratory and haemodynamic parameters(More)
This study shows for the first time that normal brain tissue toxicities after WBI can be reduced with increased dose rate. Spatial memory is preserved after WBI with mean dose rates above 100Gy/s, whereas 10Gy WBI at a conventional radiotherapy dose rate (0.1Gy/s) totally impairs spatial memory.
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