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A double-blind, cross-over comparison of Naprosyn (naproxen) 750 mg daily and Butacote (enteric-coated phenylbutazone) 300 mg daily was carried out in a multi-centre trial. Twenty-five patients, mostly male and under 40 years of age, were entered. After a 2-week period in which any existing anti-inflammatory drugs were tailed off, patients were entered into(More)
The atlantoaxial joints of a patient with lateral subluxation of the atlas were studied post mortem by dissection. There was severe erosion of the left lateral atlantoaxial joint and an asymmetrical erosion of the cartilages of the median atlantoaxial joint which prevented reduction of the lateral subluxation. The atlantoaxial ligaments were remarkably(More)
nature of the results will always be part of either choice. What this means is that, when considering whether or not to target a leader, military strike-planners must evaluate “leader targeted” against “leader not targeted” outcomes. To do so will always involve
BACKGROUND Anti-inflammatory medications are the most common treatment for rheumatic disease in Australia. Recent years have seen large increases in the use of selective cyclooxygenase-2 (COX-2) inhibitors. Predictors of use, costs and benefits of the new medications have not been evaluated. AIMS To determine trends in selective COX-2 inhibitor,(More)
We assessed the immunoglobulin secretory capacity of circulating B lymphocytes in 9 patients with classical rheumatoid arthritis (RA) before and after treatment with D-penicillamine. Peripheral blood lymphocytes (PBL) from patients with RA spontaneously synthesized more IgG and IgA than normals. The secretory rate of rheumatoid PBL could not be induced by(More)
In a 3-centre study involving 144 patients with rheumatoid arthritis (RA), a relationship between side effects from D-penicillamine and HLA antigens, allotypic markers of the IgG heavy chain (Gm) and allotypes of complement components Bf, C4A and C4B was sought. There was a significant association between proteinuria induced by D-penicillamine and the(More)