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Clinical Trial Substantiates the Predictive Value of O-6-Methylguanine-DNA Methyltransferase Promoter Methylation in Glioblastoma Patients Treated with Temozolomide
Purpose: In the setting of a prospective clinical trial, we determined the predictive value of the methylation status of the O-6-methylguanine-DNA methyltransferase (MGMT) promoter for outcome inExpand
A Vaccine against Nicotine for Smoking Cessation: A Randomized Controlled Trial
Background Tobacco dependence is the leading cause of preventable death and disabilities worldwide and nicotine is the main substance responsible for the addiction to tobacco. A vaccine againstExpand
Measuring potentially avoidable hospital readmissions.
The objectives of this study were to develop a computerized method to screen for potentially avoidable hospital readmissions using routinely collected data and a prediction model to adjust rates forExpand
Risk of falls for hospitalized patients: a predictive model based on routinely available data.
The incidence rate of falls is often used as an indicator of nursing care outcome. Comparing outcome between different settings should, however, make allowance for case mix. To measure the incidenceExpand
Altered decision‐making in multiple sclerosis: A sign of impaired emotional reactivity?
We assessed decision‐making capacity and emotional reactivity in 20 patients with multiple sclerosis (MS) and in 16 healthy subjects using the Gambling Task (GT), a model of real‐life decisionExpand
Bacteremia due to viridans streptococcus in neutropenic patients with cancer: clinical spectrum and risk factors.
Between 1988 and 1991, 26 episodes of bacteremia due to viridans streptococci occurred in 25 neutropenic patients undergoing intensive chemotherapy for hematologic malignancies. Complications relatedExpand
Admission perfusion CT: prognostic value in patients with severe head trauma.
PURPOSE To assess the prognostic value of admission perfusion computed tomography (CT) in patients with severe head trauma. MATERIALS AND METHODS This prospective study included 130 patients withExpand
Screening for excessive alcohol drinking. Comparative value of carbohydrate-deficient transferrin, gamma-glutamyltransferase, and mean corpuscular volume.
BACKGROUND Screening medical patients for excessive alcohol drinking is important because minimal intervention by physicians is effective in reducing excessive consumption. Screening tests, such asExpand
Thoracolumbar spine fractures in patients who have sustained severe trauma: depiction with multi-detector row CT.
PURPOSE To determine if multi-detector row computed tomography (CT) can replace conventional radiography and be performed alone in severe trauma patients for the depiction of thoracolumbar spineExpand
Urinary phosphate/creatinine, calcium/creatinine, and magnesium/creatinine ratios in a healthy pediatric population.
OBJECTIVE To determine reference values for urinary phosphate/creatinine (Cr) concentration ratios and to complete reference values for urinary calcium/creatinine and magnesium/creatinine ratios inExpand