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Evaluation of a combined triple method to detect causative HPV in oral and oropharyngeal squamous cell carcinomas: p16 Immunohistochemistry, Consensus PCR HPV-DNA, and In Situ Hybridization
BackgroundRecent emerging evidences identify Human Papillomavirus (HPV) related Head and Neck squamous cell carcinomas (HN-SCCs) as a separate subgroup among Head and Neck Cancers with differentExpand
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The spectrum of Spitz nevi: a clinicopathologic study of 83 cases.
OBJECTIVE To achieve a clinicopathologic classification of Spitz nevi by comparing their clinical, dermoscopic, and histopathologic features. DESIGN Eighty-three cases were independently reviewedExpand
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Field cancerization in oral lichen planus.
BACKGROUND The concept of field cancerization describes the tendency of patients with premalignant and malignant lesions of head and neck mucosal sites to develop multiple carcinomas of the upperExpand
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High prevalence of hepatitis C virus infection in patients with B‐cell lymphoproliferative disorders in Italy
Starting from the observation that a number of consecutive patients with non‐Hodgkin's lymphoma (NHL) resulted positive for hepatitis C virus (HCV) antibodies on routine testing, we set up a surveyExpand
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The role of human papillomavirus in the pathogenesis of head & neck squamous cell carcinoma: an overview
Cancer statistics report an increased incidence of OSCC and OPSCC around the world. Though improvements in screening and early diagnosis have dramatically reduced the incidence of this neoplasm inExpand
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The prognostic significance of tumor angiogenesis in nonaggressive and aggressive basal cell carcinoma of the human skin.
Basal cell carcinoma (BCC) is currently the most common cutaneous cancer found in humans. Although it generally shows a relatively benign course (BCC1), some cases of BCCs show "aggressive" behavior,Expand
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Multicenter Comparison of 22C3 PharmDx (Agilent) and SP263 (Ventana) Assays to Test PD‐L1 Expression for NSCLC Patients to Be Treated with Immune Checkpoint Inhibitors
Introduction: Among the several agents targeting the programmed cell death 1 (PD‐1) pathway, pembrolizumab is currently the only one approved for the treatment of patients with NSCLC in associationExpand
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Accelerated Bone Mass Senescence After Hematopoietic Stem Cell Transplantation
Osteoporosis and avascular necrosis (AVN) are long-lasting and debilitating complications of hematopoietic stem cell transplantation (HSCT). We describe the magnitude of bone loss, AVN and impairmentExpand
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Interobserver variability on the histopathologic diagnosis of cutaneous melanoma and other pigmented skin lesions.
PURPOSE To assess the interobserver agreement on the diagnosis and classification of cutaneous melanoma. MATERIALS AND METHODS A set of 140 slides of cutaneous melanoma, including a small subset ofExpand
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Dermatoscopic pitfalls in differentiating pigmented Spitz naevi from cutaneous melanomas
Epiluminescence microscopy (ELM, skin surface microscopy, dermoscopy, dermatoscopy) is a valuable method for improving the diagnostic accuracy in pigmented skin lesions. Specific ELM criteria areExpand
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