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The calcium‐binding proteins MRP8 and MRP14 form a membrane‐associated heterodimer in a subset of monocytes/macrophages present in acute but absent in chronic inflammatory lesions
Monocytes/macrophages expressing an epitope recognized by a monoclonal antibody 27E10 are present in acute but are absent in chronic inflammatory disorders. This report shows that the 27E10 antigenExpand
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Rapid uptake of gold nanorods by primary human blood phagocytes and immunomodulatory effects of surface chemistry.
Nanoparticle-based in vivo applications should consider the omnipresence of the phagocytes in the bloodstream and tissue. We have studied the nanoparticle uptake capacities of the most importantExpand
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A skin-like cytochrome P450 cocktail activates prohaptens to contact allergenic metabolites.
Allergic contact dermatitis is a complex syndrome representing immunological responses to cutaneous exposure to protein-reactive chemicals. Although many contact sensitizers directly can elicit thisExpand
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Cytochrome P450 1B1: a major P450 isoenzyme in human blood monocytes and macrophage subsets.
In this study, cytochrome P450 (CYP; EC 1.14.14.1)-dependent activities and P450 isoenzyme patterns were determined in human monocytes and macrophages, which play a major role in antigen processingExpand
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Active influx transport is mediated by members of the organic anion transporting polypeptide family in human epidermal keratinocytes.
Normal human epidermal keratinocytes have been shown to express a cell-type-specific pattern of extrahepatic cytochrome P450 enzymes and efflux transport proteins showing that these cells metabolizeExpand
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Inducing healing-like human primary macrophage phenotypes by 3D hydrogel coated nanofibres.
Immune cells are present in the blood and in resident tissues, and the nature of their reaction towards biomaterials is decisive for materials success or failure. Macrophages may for example beExpand
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The chorioallantoic membrane of the chick embryo as a simple model for the study of the angiogenic and inflammatory response to biomaterials
Angiogenesis is essential in wound healing and a common feature in chronic inflammation which is crucially involved in the biological response to biomaterials. A useful system to evaluate theExpand
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Differential expression of influx and efflux transport proteins in human antigen presenting cells
Abstract:  Human macrophages (MΦ) express cytochrome P450 enzymes verifying their capacity to metabolize a variety of endogenous and exogenous substances. Here we analysed the mRNA and proteinExpand
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Phagocytosis independent extracellular nanoparticle clearance by human immune cells.
It has recently been discovered that human immune cells, especially neutrophil granulocytes, form neutrophil extracellular traps (NETs) that abolish pathogens. Our study provides evidence thatExpand
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Glucocorticoid-induced appearance of the macrophage subtype RM 3/1 in peripheral blood of man.
The effect of intravenous administration of the glucocorticoid prednylidene on the macrophage subtype RM 3/1 in the peripheral blood of man was studied. Injection of 60 mg steroid resulted in anExpand
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